Study Links Excess of Sugar to Diabetes

First Posted: Feb 02, 2013 12:03 PM EST
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Sugar can be as dangerous as cigarettes and alcohol as it is one of the primary sources of calories for Americans. It offers a devastating toll on health as it is a largest contributor of obesity and other chronic diseases such as diabetes.

Apart from obesity and diabetes, a latest study shows a strong correlation between sugar and cancer. If you want to cut yourself from these diseases then you have to limit your daily sugar consumption. This comes as a warning for the diabetic population who are at a higher risk of suffering from pancreatic or colon cancer.

The study was conducted by the scientists at the University Rey Juan Carlos in Madrid and was led by Dr. Custodia Garcia-Jimenez. They have devised a mechanism that links obesity and diabetes with cancer. They studied how the intestinal cells respond to sugars and immediately respond to the pancreas to release the insulin. Insulin helps in controlling the blood sugar levels.

The protein beta-catenin was studied because this controls the intestinal cells ability to produce a hormone called GIP. GIP enhances insulin release by the pancreas. 

Beta catenin's activity is totally dependent on sugar levels. So increases activity of Beta Catenin is a causes development of major cancers and make normal cells immortal, indicating the early stages of cancer progression.

Colin Goding, Professor of Oncology at the University of Oxford, UK was quoted in Medicalxpress stating, "This study identifies a key molecular mechanism through which high blood glucose would predispose to cancer. It opens the way for potential novel therapies aimed at reducing cancer risk in the obese and diabetic populations."

The study was published in the journal Molecular Cell.

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