Health & Medicine

What is DNA Testing and How Does it Works?

Ernest Hamilton
First Posted: Sep 12, 2019 09:35 AM EDT

DNA testing is a handy procedure for validating a stated (alleged) biological relationship when no other form of credible evidence is available. It involves obtaining DNA from a blood sample or tissue sample to identify specific proteins, chromosomes, or genes, including those that are faulty (mutations). In most cases, DNA testing is useful in identifying genetic lineage; however, it can also help in ruling out or confirming an inherited genetic disorder, assessing the risk of passing on or developing a genetic disease, and determining which drug will prove the most effective based on an individual's genetic profile. With the advancement in medical science and technology, several hundred DNA tests are available. The tests can be performed on hair, bone, body tissues, saliva, urine, or blood. 

What is the purpose of DNA testing? 

Discoveries in DNA are pushing the way we think about ourselves, our overwhelming similarities, our essential differences, how we act, and more. Your doctor may recommend a DNA test for reasons related to treatment, diagnosis, or prevention of any disease. Moreover, DNA testing is also helpful in legal investigations. 

How does DNA testing work? 

Every cell in the human body contains chromosomes, genes, and deoxyribonucleic acid (DNA). Each serves an interrelated and specific function. 

What is the procedure? 

  1. Blood draw - a needle is inserted into the vein by a phlebotomist extracting 1-3 milliliters of blood. 

  2. Buccal smear - also known as a cheek swab, it is performed by rubbing cotton along the inside of the cheeks. 

  3. Saliva sample - you are asked to spit in a sterile container tube to fill with your saliva.

  4. Amniocentesis - it is the procedure of obtaining a small amount of amniotic fluid sample. A hollow, thin needle is inserted through the abdominal wall and into the uterus for collecting the sample 

With DNA tests, you can discover your family roots and migration history, and even discover DNA relatives of yours from different parts of the world. 

In addition to that, DNA tests helps understanding whether you have a health problem or carry a genetic disease. There is lots of online information about how to get the most out of your results.

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