Colon Cancer: Excess Body Weight Increases Disease Risk

A report from the World Health Organization (WHO) just showed us that eating processed meats can increase the risk of colon cancer. Now, new findings presented at the 23rd United European Gastroenterology Week (UEG Week 2015) in Barcelona, Spain, reveal that excess body weight can also increase colon cancer risk.

Researchers at the Institute of Cellular Medicine at Newcastle University in the United Kingdom found an overall relative risk of colorectal cancer (CRC) per 5 unit increase in body mass index (BMI).

The study showed how for men in particular, increasing waist circumference in middle age is linked to an increased risk of bowel cancer. In fact, colorectal cancer risk was 60 percent higher in men who gained at least 10 cm in the waist circumference over 10 years, according to researchers, which many believe has to do with the inflammation that's linked to obesity.

The study also found that those with Lynch syndrome were at an increased risk for CRC. Lynch syndrome, often referred to as hereditary nonpolyposis colorectal cancer (HNPCC), is an inherited disorder that increases the risk of certain types of cacner--particularly cancers of the colon and rectum.

This study specifically showed that CRC risk further increases in Lynch syndrome patients of heavier weight. Furthermore, researchers also pointed out that for obese patients without Lynch syndrome, the CRC risk is doubled.

While genetic components do play a part in many types of cancer risks, improving lifestyle habits through healthy dietary choices, physical activity and other means can help to lower risk and even prevent certain health issues, according to researchers.

"This is a very intriguing finding" said study author John Mathers, Professor of Human Nutrition from the Institute of Cellular Medicine, in a news release "which suggests that dietary and other anti-inflammatory agents might be beneficial in reducing CRC risk in people with obesity."

"Bowel cancer is strongly associated with age, obesity and diet - and is driven by inflammation", Mathers added. "We can now give the public clear advice on the benefits of staying physically active, eating a healthy diet and avoiding weight gain to lower CRC risk as we get older."

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