Children With Older Parents Have Healthier Metabolism

The genetic components based on metabolism are often out of our control. Yet recent findings published in the American Journal of Human Biology reveal that children born to older parents are more likely to have lower blood pressure, more favorable cholesterol levels and improved glucose metabolism, overall.

However, researchers reiterate that it's unclear whether the beneficial effect found in the study was due to having an older mother, father or both.

"We studied 73 men aged 46.0±5.4 years, who were overweight (body mass index, BMI 25-30 kg/m2) but otherwise healthy. Insulin sensitivity was assessed by the Matsuda method from an oral glucose tolerance test. Other assessments included dual-energy X-ray absorptiometry-derived body composition, lipid profile, 24-hour ambulatory blood pressure, and carotid intima-media thickness. Maternal and paternal ages were highly correlated (r = 0.71; P < 0.0001), and the main parameter of interest in this study was the mean parental age at childbirth (MPAC), calculated as the average of maternal and paternal ages," researchers noted, in a news release. 

"Increasing parental age at childbirth was associated with a more favorable metabolic phenotype in overweight middle-aged males," they concluded. "However, it is unknown whether the effect was maternal, paternal, or both. Future studies on the effects of parental age at childbirth on the metabolism of males and females across the BMI range are required."