Building Better, Safer Cancer and HIV Medications

A recent study examines 1,2,3-triazoles that can be synthesized through a metal-free reaction with easy to access ingredients. As synthesizing this compound had been difficult in the past because many researchers are dependent on primarily harmful and heavy metals that could interrupt the process, they have now successfully produced excessive compounds that could help with certain health treatments in the future. 

"We were able to develop a reaction that provided a good yield, high regioselectivity and easy access to diversely functionalized 1,2,3-triazoles," said corresponding author Prof. Dr. Wim Dehaen, in a news release. "In other words, the reaction produces plenty of the compounds we're looking for, does so reliably without unwanted or unexpected outcomes, and does this in a way that makes it easy for us to isolate the compound. This makes our method highly desirable."

"Moving forward, we will focus on expanding the chemistry developed here to other new reactions while also exploring their possible applications in pharmaceutical as well as supra-molecular sciences," added lead author Dr. Joice Thomas.

More information regarding the findings can be seen via the journal Angewandte Chemie.